After the death of a superhero she actually liked, Harley Quinn is struggling to find joy wreaking havoc in an already supremely messed-up world. She's even debating becoming a real, true hero and leaving her chaotic life of crime behind. But her partner in crime, Poison Ivy, is not sold. And when the Floronic Man shows up hell-bent on harming Ivy, the duo has to hit the streets to avoid him. Can Harley and Ivy survive this wild road trip?